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Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
1110007C02Rik; AI480648; Arsb; Arylsulfatase B; Arylsulfatase B (MPS VI); arylsulfatase B complex; arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; As1; As-1; As-1r; As1-r; As-1s; As1-s; As-1t; As1-t; ASB; Asr-1; Ast-1; G4S; MPS6; N-acetylgalactosamine-4-sulfatase
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